Recent Patents on Permeation Enhancers for Drug Delivery Through Nails
نویسندگان
چکیده
منابع مشابه
Intestinal permeation enhancers for oral peptide delivery.
Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation enhancement action of over 250 PEs that have been tested in intestinal delivery models. In depth analysis of pre-clinical data is presented for PEs as components of proprietary delivery systems that have progressed t...
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Certain agents that enhance drug transport through the skin, including surfactants, bile salts, and fatty acids, have been shown to exert a similar effect on the oral mucosa. Oral drug delivery offers an attractive method of needle-free drug administration. Unfortunately, oral delivery is often hampered by the poor permeability of drugs across the intestinal epithelium. Although several single ...
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The present invention is in the field of bioinformatics, particularly as it pertains to gene prediction. More specifically, the invention relates to the probabilistic analysis of nucleic acid sequences for the determination of coding features, including determination of state probabilities for each nucleotide in a nucleic acid sequence, determination of coding strand, determination of open read...
متن کاملInfluence of Chemical Permeation Enhancers on the in vitro Skin Permeation of Minoxidil through Excised Rat Skin: A Mechanistic Study
Abstract: Minoxidil, a pyrimidine derivative (2, 4-diamino-6-piperidinopyrimidine-3-oxide) is the only topical medical treatment with proven efficacy for the treatment of Androgenetic alopecia that shown low skin penetration and bioavailability. The main aim of this research was to investigate the effect of some permeation enhancers on the in vitro skin permeability of minoxidil . Minoxid...
متن کاملeffect of permeation enhancers in the mucoadhesive buccal patches of salbutamol sulphate for unidirectional buccal drug delivery
the purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (ss) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. the influence of various permeation enhancers, such as dimethyl sul...
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ژورنال
عنوان ژورنال: Recent Patents on Drug Delivery & Formulation
سال: 2020
ISSN: 1872-2113
DOI: 10.2174/1872211313666191030155837